Subject of research – a set of relations that arise in the process of improving the organizational and economic mechanism of regulation of domestic fisheries and aquaculture in Ukraine and the introduction of practical proposals for the action of the mechanism of traceability of biological raw materials of water origin. The purpose of the article is the development of scientific and methodological and practical recommendations for ensuring the organizational and economic mechanism of regulation of fisheries and aquaculture taking into account the traceability of biological raw materials of water origin in Ukraine. The methodology of the work – the theoretical and methodological basis of the study is a system of general scientific and special methods of scientific knowledge, the fundamental provisions of modern economic theory. In the article methods are used: historical-logical and analysis and synthesis – when formulating conclusions and proposals in the formation of scientific and methodological foundations with the aim of consistently developing proposals in adapting the regulatory component of the organizational and economic mechanism for ensuring the traceability of biological raw materials of water origin. The results of the work – proposed to practical application of the latest approaches to ensure the mechanism of traceability of biological raw materials of water origin. The emphasis is placed on the fact that the stock of aquatic biological resources in natural waters is an overriding factor in global food security. It has been proved that with the development of technologies for extraction, catching fish and other aquatic living resources, ensuring a stable production volume every year leads to more effective control and implementation of regulatory measures. Conclusions – in the management of fisheries, one of the factors that greatly influences the effectiveness of regulation is the illegal, unrecognized, uncontrolled fishing, and aquaculture – the need to improve the system for collecting information from producers of products is in the foreground. The measures of regulation and methods of introduction of an effective mechanism of traceability of biological raw materials of water origin and improvement of reporting 1A-fish (annual).